Ensuring the accuracy and comprehensiveness of Minimum Data Set (MDS) assessments is crucial for maintaining the quality of care in healthcare settings, particularly in long-term care facilities. The MDS Significant Change Checklist serves as an indispensable tool for healthcare professionals to identify and track significant changes in a resident’s condition. This checklist aids in promoting patient-centered care, enhancing communication among healthcare teams, and facilitating timely interventions. Here is a list of key elements encompassed within the MDS Significant Change Checklist: