Vascular Ehlers-Danlos syndrome (vEDS) is a rare, life-threatening disorder that affects the blood vessels. It is caused by a mutation in the COL3A1 gene, which encodes the collagen type III protein. This protein is important for the structure and strength of blood vessels.

People with vEDS have weakened blood vessels that are prone to rupture. This can lead to life-threatening bleeding and organ damage. There is no cure for vEDS, but early diagnosis and treatment can help prevent serious complications.